Consequences of Obesity Obesity is a complex health issue to address. Obesity results from a combination of causes and contributing factors, including individual factors such as behavior and genetics. Behaviors can include dietary patterns, physical activity, inactivity, medication use, and other exposures. Additional contributing factors in our society include the food and physical activity environment, education and skills, and food marketing and promotion.
Researchers around the world are working to find better ways to preventdetectand treat breast cancer, and to improve the quality of life of patients and survivors. Some of the many active areas of research include: Breast cancer causes Causes and treatment of metastatic breast cancer Reducing breast cancer risk Managing ductal carcinoma in situ DCIS New lab tests for breast cancer New imaging tests for breast cancer Breast cancer treatment Supportive care Breast cancer causes Studies continue to uncover lifestyle factors and habits, as well as inherited genes, that affect breast cancer risk.
Here are a few examples: Several studies are looking at the effect of exercise, weight gain or loss, and diet on risk. Studies on the best use of genetic testing for breast cancer mutations continue at a rapid pace. Scientists are exploring how common gene variations small changes in genes that are not as significant as mutations may affect breast cancer risk.
Gene variants typically have only a modest effect on risk, but when taken together they could possibly have a large impact. Possible environmental causes of breast cancer have also received more attention in recent years. While much of the science on this topic is still in its earliest stages, this is an area of active research.
Reducing breast cancer risk Researchers continue to look for medicines that might help lower breast cancer risk, especially women who are at high risk. Hormone therapy drugs are typically used to help treat breast cancer, but some might also help prevent it. Tamoxifen and raloxifene have been used for many years to prevent breast cancer.
More recent studies with another class of drugs called aromatase inhibitors exemestane and anastrozole have shown that these drugs are also very effective in preventing breast cancer Other clinical trials are looking at non-hormonal drugs for breast cancer reduction.
Drugs of interest include drugs for osteoporosis and bone metastases, COX-2 inhibitors, non-steroidal anti-inflammatory drugs, and statins used to lower cholesterol. When breast cancer spreads, it often goes to the bones. Some drugs that help treat the spread of cancer to the bones such as bisphosphonates and denosumabmight also help reduce the chances of the cancer coming back.
Studies done so far seem to suggest that postmenopausal women may benefit the most from giving these bone-modifying drugs after breast surgery, but more studies are needed to say for sure. This type of research takes many years.
It might be some time before meaningful results on any of these compounds are available.
In other women, though, the cells just stay within the ducts and never invade deeper or spread to lymph nodes or other organs. The uncertainty about how DCIS will behave can make it hard to choose the best treatments. Researchers are looking for ways to help with these challenges.
Decision aids are another approach. They ask a woman with DCIS questions that help her decide which factors such as survival, preventing recurrence, and side effects she considers most important in choosing a treatment. New lab tests Tests for circulating tumor cells CTCs Researchers have found that in many women with breast cancer, cells may break away from the tumor and enter the blood.
These circulating tumor cells CTCs can be detected with sensitive lab tests.
Some studies are looking at if these CTCs can be removed and then tested in the lab to determine which specific anticancer drugs will work on the tumor. New imaging tests Newer imaging methods are now being studied for evaluating breast changes that may be cancer. Scintimammography molecular breast imaging In this test, a slightly radioactive drug called a tracer is injected into a vein.
The tracer attaches to breast cancer cells and is detected by a special camera. This technique is still being studied to see if it will be useful in finding breast cancers. Some doctors believe it may be helpful in looking at suspicious areas found by regular mammograms, but its exact role is still unclear.
Current research is aimed at improving the technology and evaluating its use in specific situations such as in the dense breasts of younger women.
Breast cancer treatment Chemotherapy It is known that chemotherapy can be helpful for many breast cancer patients. But predicting who will benefit the most or the least is still being studied.
Sometimes there are significant side effects long- and short-term from chemotherapy, so having tests that can determine who really needs chemo would be useful. Many studies are being done to evaluate different tests that can more accurately tell which patients would benefit from chemo and which patients could avoid it.
Oncoplastic surgery Breast-conserving surgery lumpectomy or partial mastectomy can often be used for early-stage breast cancers. For larger tumors, it might not even be possible, and a mastectomy might be needed instead. Some doctors are addressing this problem by combining cancer surgery and plastic surgery techniques, known as oncoplastic surgery.
This typically involves reshaping the breast at the time of the initial surgery, such as doing a partial breast reconstruction after breast-conserving surgery or a full reconstruction after mastectomy.DIETARY GUIDELINES FOR DIABETES ] The REAL cause of Diabetes (Recommended),Dietary Guidelines For Diabetes Its an enlightening process finding your personality (and recognising people friends and family) plus simple matter to start treatment whenever you get the kind of Remedies%().
Hi, AnnaM, I’m guessing someone could argue (and probably will) that since coconut is paleo and butter is not, the lauric acid content of the coconut (almost 50% of total fat) simply must be superior to the comparable myristic-palmitic acid content of the butter.
Thank you so much everyone for your comments and suggestions. I was curious to see how others would respond to this problem. This post is a followup to my a senario that I was presented with – a new client who has been following a low carb diet and is doing 5 – 6 .
07 Mark Lynas from Oxford Farming Conference on Vimeo.. I want to start with some apologies. For the record, here and upfront, I apologise for having spent several years ripping up GM crops.
- Dietary Guidelines for North Americans and Suggestions for Food Choices In today's society nearly everyone follows some kind of dietary guidelines. Whether it is in the goal of losing weight, gaining weight or just simply to maintain it, people are jumping onto the dietary band-wagon.
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